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SKU
AZ-TB500-10
TB-500 10mg
In Stock
Original price was: $80.00.$70.00Current price is: $70.00.
In stock
Fulfillment Timing Based on Inventory and Account Status.
TB-500 10mg
HPLC Certified
CAS #
885340-08-9
M.W.
889.01
Formula
C38H68N10O14
- PURITY
- ≥99%
RUO
- (Research Use Only)
Specs:
- Amount: 10mg | Format: Lyophilized Powder | Container: 3mL Vial | Storage: 2-8°C | Type: Single Peptide | Research Alias: TB4 / Thymosin Beta-4 | Research Category: Cytoskeletal Pathway Research
Buy TB-500 (Thymosin Beta-4) 10mg | 99% Purity USA-Made | AZOTH
What Is TB-500?
TB-500 is a synthetic version of Thymosin Beta-4, a naturally occurring peptide found in platelets and most human and animal cells. This synthetic fragment consists of a short chain of amino acids and has drawn significant attention in laboratory research focused on tissue repair, cell migration, and wound healing. Researchers studying tissue regeneration have documented TB-500’s role in promoting cell migration to injured areas, supporting angiogenesis, and regulating actin, a protein central to cell movement and structural integrity. At AZOTH, we supply pharmaceutical-grade TB-500 peptide manufactured to 99%+ purity, backed by third-party certificate of analysis (COA) documentation for each batch, intended exclusively for licensed researchers and laboratory professionals.
How Does TB-500 Work? Mechanisms Explored in Preclinical Research
TB-500 does not appear to act through a single receptor. Instead, preclinical research suggests it functions through actin regulation, a mechanism that governs cell migration and cell proliferation across multiple tissue types in animal models. Actin Regulation and Cell Migration TB-500 binds to actin, the building block responsible for forming the cytoskeleton within cells. This interaction supports cell migration toward damaged tissues, a process that researchers consider foundational to the body’s natural healing processes in preclinical wound healing models. Angiogenesis and Blood Flow Animal studies have shown that TB-500 promotes the formation of new blood vessels, improving blood flow to injured areas. This vascular effect is closely tied to tissue regeneration, particularly in models involving muscle and connective tissue injury. Endothelial Cell Differentiation Research has also explored TB-500’s role in endothelial cell differentiation, a process relevant to how new vascular structures form at sites of tissue injury in animal models. Anti-Inflammatory Effects Preclinical studies point to TB-500’s anti-inflammatory effects, including a reduction in chronic inflammation markers observed in animal models following tissue injury.
TB-500 Peptide Research Applications
Tissue Repair and Injury Recovery
TB-500 has become a focus of research examining tissue repair following sports injuries and general injury recovery in animal models. Its documented role in cell migration allows repair cells to reach injured areas more efficiently, a process considered central to the healing process. Peptide therapy research combining TB-500 with other compounds is a common area of interest for researchers examining systemic muscle repair.
Post Surgical Recovery Research
A notable research application for TB-500 involves post surgical recovery models. Preclinical studies suggest TB-500 may reduce scar tissue formation after surgery, supporting tissue healing in damaged tissues following surgical procedures. Researchers examining patients recovering from procedures involving connective tissue often reference TB-500 alongside BPC-157 in combination protocols.
BPC-157 and TB-500 Combination Research (Wolverine Stack)
BPC-157 and TB-500 are frequently studied together in what researchers commonly refer to as the wolverine stack, a peptide combination explored for localized and systemic tissue repair. BPC-157 is primarily associated with localized healing of tendons and ligaments, while TB-500 is considered better suited for systemic muscle repair and scar tissue reduction. Both BPC-157 and TB-500 are unapproved by the FDA for human use, and no large-scale human trials currently validate the efficacy of either compound.
Wound Healing and Reduced Inflammation
Animal studies have documented TB-500’s contribution to wound healing through mechanisms including reducing inflammation and supporting immune response regulation at injury sites. Researchers examining chronic inflammation models have observed that TB-500’s anti-inflammatory effects work alongside its cell migration properties to support faster healing in preclinical settings.
Research Summary: What the Preclinical Science Shows on TB-500
Preclinical research on TB-500 spans regenerative medicine, sports injury models, and post surgical recovery research. Below is a summary of key research areas documented in animal studies.
| Research Area | Model | Key Findings |
|---|---|---|
| Tissue Regeneration | Animal wound models | Increased cell migration and tissue repair observed at injury sites |
| Angiogenesis | Animal ischemia models | Enhanced blood vessel formation and blood flow to damaged tissues |
| Post Surgical Recovery | Rodent surgical models | Reduced scar tissue formation documented in preclinical studies |
| Chronic Inflammation | Various animal tissues | Reducing inflammation and anti-inflammatory effects observed |
| Actin Regulation | Cell culture models | TB-500 binding to actin supports cell proliferation and cell movement |
TB-500 is classified as a research chemical and is not FDA approved as a prescription medication. TB-500 is also banned by the World Anti-Doping Agency, a regulatory status relevant to athletes and sports injuries research. No large-scale human trials currently exist to confirm efficacy, and long-term safety data for TB-500 remains limited. Reported side effects in available literature include injection-site reactions and lethargy, underscoring the importance of prioritizing patient safety in any research protocol.
Why Researchers Choose AZOTH for TB-500 Peptide
Quality and purity concerns are common across TB-500 products sold online, making rigorous testing essential for laboratory research.
- Verified 99%+ purity via third-party testing
- USA-manufactured under strict quality protocols
- Certificate of Analysis available for every batch
- Lyophilized powder format for shelf stability
- Independent verification of identity and purity for informed decisions
Storage and Handling
TB-500 is supplied in lyophilized (freeze-dried) powder form. Store at 2-8°C in a cool, dry environment away from light and moisture. After reconstitution with bacteriostatic water, keep refrigerated and use according to your laboratory research protocol.
Legal Disclaimer
TB-500 sold by AZOTH is intended for laboratory and in vitro research use only. It is not approved by the Food and Drug Administration (FDA) for human consumption, medical use, diagnostic procedures, or veterinary use. This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease or medical condition. Bodily introduction of any kind into humans or animals is strictly prohibited by law. All purchasers must be licensed researchers or qualified laboratory professionals.
Referenced Citations
| Research Findings | Journal | Data | Source Link |
|---|---|---|---|
| 1. Goldstein AL, et al. “Thymosin beta 4: actin-sequestering protein moonlights to repair injured tissues.” | Trends Mol Med | 2005; 11(9):421-429 | pubmed.ncbi.nlm.nih.gov |
| 2. Sosne G, et al. “Thymosin beta 4 promotes corneal wound healing and modulates inflammatory mediators in vivo.” | Exp Eye Res | 2007; 84(4):663-669 | pubmed.ncbi.nlm.nih.gov |
| 3. Philp D, et al. “Thymosin beta 4 promotes angiogenesis, wound healing, and hair follicle development.” | Mech Ageing Dev | 2004; 125(2):113-115 | pubmed.ncbi.nlm.nih.gov |
| 4. ClinicalTrials.gov reference on peptide research compound safety data. | ClinicalTrials.gov | N/A | clinicaltrials.gov |
Featured Research Compounds
Original price was: $100.00.$90.00Current price is: $90.00.
Original price was: $100.00.$90.00Current price is: $90.00.
Original price was: $100.00.$90.00Current price is: $90.00.
Original price was: $100.00.$90.00Current price is: $90.00.
Research use only
All AZOTH products are intended solely for laboratory research, analytical, and scientific use. Products are not for human consumption, human use, veterinary use, diagnostic use, therapeutic use, or administration of any kind.